Keywords: Alzheimer's Disease, Degenerative
Motivation: Improve detection sensitivity while maintaining reasonable scan times.
Goal(s): Assess how the newly available, 3D Echo Planar Imaging (EPI), performs when compared to 2D GRE in detection of cerebral microhemorrhages (mH).
Approach: Conducted on 15 patients with confirmed mHs, and independently reviewed the 2D GRE and 3D EPI images to assess the number and distribution of definite mH and possible mH.
Results: 3D EPI sequence allowed the detection of 26 definite and 3 possible mHs, compared to 17 definite and 8 possible mHs identified by the 2D GRE sequence. 3D EPI was comparable to 2D GRE at approximately 1 minute of scan time.
Impact: The introduction of 3D EPI as a fast, highly sensitive pulse sequence for detecting microhemorrhages could aid in MRI-based diagnosis in neurodegenerative diseases.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords