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Abstract #1817

Relaxation compensation in preparation-based cardiac B1+ mapping

Hanna Post1, Maša Božić-Iven1, Paulina Šiurytė1, Yi Zhang1, Chiara Coletti1, Alexandru Cernicanu2, Christal van de Steeg Henzen3, Qian Tao1, and Sebastian Weingärtner1
1TU Delft, Delft, Netherlands, 2Philips Benelux, Eindhoven, Netherlands, 3Holland PTC, Delft, Netherlands

Synopsis

Keywords: Pulse Sequence Design, Cardiovascular, B1 mapping

Motivation: Cardiac MR at high field strengths offers increased SNR, but suffers from RF field inhomogeneities. Preparation-based B1+ mapping techniques are promising for robust mapping but are susceptible to confounders.

Goal(s): Zero-degree hyperbolic secant (HS) pulses are evaluated to mitigate bias due to T1ρ relaxation in preparation-based B1+ mapping in the heart.

Approach: A zero-degree HS pulse is introduced as a baseline measurement and tested in simulations and phantoms. B1+ map quality is evaluated in vivo.

Results: Thorough compensation is achieved with confounder correction in simulations and reduced error slope in phantom. Preparation-based B1+ mapping achieves superior in vivo mapping quality compared with DREAM.

Impact: Confounder-corrected preparation-based B1+ mapping enables robust B1+ map quality in the human heart. Confounder correction can help to further reduce bias, which may be particularly important for assessing B1+ trends across tissue boundaries with different T1rho times.

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Keywords