Keywords: Quantitative Imaging, Quantitative Imaging, Missed triggering, T1 mapping, Myocardial T1, Cardiac MRI
Motivation: In cardiac MRI, the impact of ECG missed-triggering events on MOLLI 5(3)3 T1 mapping accuracy has not been fully studied despite its common use in clinical service.
Goal(s): This work investigated how missed-triggering affects myocardial T1 measurements at normal heart rates.
Approach: We developed a framework to simulate missed-triggering events along the T1 inversion recovery curve in phantom data.
Results: Specific combinations of missed-triggering events resulted in significant T1 estimation errors. The maximum absolute T1 measurement error across all missed-triggering events stayed below 13%, suggesting MOLLI 5(3)3 is a robust technique for cardiac T1 mapping at normal heart rates.
Impact: The robustness of MOLLI 5(3)3 cardiac T1 mapping in the presence of ECG missed-triggering events at normal heart rates has been investigated, allowing clinicians to gain an insight into its diagnostic value, where ECG is not reliable due to missed-triggering.
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