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Abstract #1821

4D cardiac QSM acquisition and reconstruction of Free-Breathing ECG Gated Data: Initial Feasibility

Gowtham Baskar1,2,3, Myat Thein1,3, Jouke Smink4, Nautoshi Hibino5, Martin Prince3, Yi Wang3, Alexey Dimov3, and Keigo Kawaji1
1Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States, 2Computer Science, Illinois Institute of Technology, Chicago, IL, United States, 3Radiology, Weill Cornell Medicine, New York City, NY, United States, 4Philips, Best, Netherlands, 5Surgery, University of Chicago Medical Center, Chicago, IL, United States

Synopsis

Keywords: Quantitative Imaging, Quantitative Susceptibility mapping, Cardiac MRI, 4D Imaging, Magnetic Susceptibility

Motivation: Quantitative Susceptibility Mapping (QSM) faces challenges in cardiac imaging due to air-tissue interfaces and respiratory motion mitigated by 4D gating.

Goal(s): This approach aims to enhance cardiac susceptibility mapping across the full cardiac cycle, achieving artifact reduction for improved clinical utility in CMR.

Approach: A free-breathing, navigator-gated 4D cardiac QSM sequence was acquired on eight swines using a multi-echo GRE acquisition with CS-SENSE acceleration. MEDI reconstruction was performed on all cardiac phases.

Results: Reconstructed susceptibility maps referenced to the porcine back muscle demonstrated artifact suppression in seven out of nine cardiac regions.

Impact: This study establishes initial feasibility for a 4D free-breathing QSM approach in cardiac imaging, overcoming artifacts due of air-tissue interfaces and demonstrating robustness in mapping across cardiac phases.

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