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Abstract #1828

Simultaneous 3D T1- and T2-mapping of abdominal aortic aneurysms with black blood and fat suppression

Wilhelm Stehling1, Eva Aalbregt1,2, Myrte Wennen1, Eric Schrauben1, Pim van Ooij1, Kak Khee Yeung2, Aart Nederveen1, and Oliver Gurney-Champion1
1Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, Netherlands, 2Vascular Surgery, Amsterdam University Medical Center, Amsterdam, Netherlands

Synopsis

Keywords: Quantitative Imaging, Relaxometry

Motivation: An abdominal aortic aneurysm (AAA) poses a risk of rupture, leading to high mortality rates. T1- and T2- may be biomarkers for rupture.

Goal(s): To implement and test a high-resolution, and motion-robust T1- and T2-mapping strategy that includes blood and fat suppression.

Approach: A combined 3D T1- and T2-mapping approach was developed and tested in a phantom. T1- and T2-values of 16 AAA-patients were computed and compared with the aneurysm diameter.

Results: The proposed protocol successfully generated volumetric T1- and T2-maps of the aortic wall. The median T1- and T2-values obtained from AAA patients did not correlate with aneurysm diameter.

Impact: An abdominal aortic aneurysm poses a risk of rupture, leading to high mortality rates. The proposed black-blood fat suppressed simultaneous T1- and T2-mapping approach in AAAs may provide additional biomarkers to estimate rupture risk.

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