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Abstract #1868

Free-running 4D lung imaging at 0.55T using UTE-bSSFP with intra-bin correction and inter-bin compensation of respiratory motion

Adele LC Mackowiak1, Stanislas Rapacchi1, Guillaume Fahrni1, Chiara Pozzessere1, Jean-Baptiste Ledoux1,2, Matthias Stuber1,2, David C Rotzinger1, and Christopher W Roy1
1Department of Radiodiagnosis & Interventional Radiology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland, 2Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

Synopsis

Keywords: Lung, Low-Field MRI, free-breathing, UTE, respiratory motion, 0.55T, high-resolution

Motivation: To strenghten the validation of free-running UTE imaging at low field, as a non-invasive, radiation-free tool for pulmonary imaging.

Goal(s): To evaluate the effectiveness of a 3D radial UTE-bSSFP sequence for high-resolution respiratory-resolved lung imaging at 0.55T.

Approach: A bSSFP-UTE sequence following a double-phyllotaxis trajectory was acquired at resolutions 1.25mm3 and 0.98mm3, on a phantom and n=6 healthy volunteers under free-breathing. Respiratory-resolved images at two resolutions and acquisition times were compared through metrics of interface sharpness, contrast ratio, and apparent SNR.

Results: Excellent pulmonary vessel delineation was obtained, with no siginificant differences in sharpness or apparent SNR between different spatial resolutions.

Impact: This study further validates low-field UTE lung imaging, achieving sub-millimetric 4D resolution without significant loss of pulmonary vessel sharpness or apparent SNR when accelerating two-fold, thanks to a powerful respiratory-resolved reconstruction, suggesting strengthened clinical translation.

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Keywords