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Abstract #1871

Free-Breathing Functional Lung Imaging at 0.6T compared to 1.5T

Efe Ilicak1,2, Ece Ercan3, Yiming Dong2, Marius Staring1, Andrew Webb2, Matthias J.P. van Osch2, Peter Börnert2,4, and Martijn Nagtegaal 2
1Department of Radiology, Division of Image Processing, Leiden, Netherlands, 2Department of Radiology, C.J. Gorter MRI Center, Leiden, Netherlands, 3MR Clinical Science, Best, Netherlands, 4Philips Innovative Technologies, Hamburg, Germany

Synopsis

Keywords: Lung, Lung, Signal Modeling, Bioeffects & Magnetic Fields

Motivation: Non-contrast-enhanced pulmonary functional imaging is a promising technique. However, it is limited by rapid signal decay from susceptibility differences within the lung parenchyma.

Goal(s): To assess the image quality of pulmonary functional maps acquired at 0.6T and 1.5T using the dynamic mode decomposition (DMD) MRI technique.

Approach: We acquired free-breathing images using balanced steady-state free precession sequences at both field strengths. The images were non-rigidly registered using Elastix, and functional maps were derived using DMD.

Results: Preliminary findings demonstrate that mid-field MRI can successfully acquire pulmonary functional information, with quantitative results indicating improved functional map quality at 0.6T.

Impact: We investigate the usefulness of 0.6T MRI for free-breathing functional lung imaging. Our findings demonstrate improved image quality compared to 1.5T, with improved tissue-background contrast and homogeneity of functional maps, underscoring the system's robustness and potential for non-invasive pulmonary imaging.

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