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Abstract #1878

Ultrashort echo-time (UTE) functional lung imaging for fractional ventilation quantification: breath-hold vs. free-breathing

Huilou Liang1, Ruzhi Zhang1, and Pu-Yeh Wu1
1GE HealthCare MR Research, Beijing, China

Synopsis

Keywords: Lung, Lung

Motivation: Ultrashort echo-time (UTE) technique has recently gained attention in functional lung imaging for deriving quantitative maps including fractional ventilation (FV). Breath-hold UTE method can be easily utilized in clinical practice. However, failures in maintaining breath-hold often occur in clinical settings.

Goal(s): To propose a free-breathing UTE method based on respiratory gating and compare its performance with breath-hold UTE method.

Approach: Both breath-hold and free-breathing UTE methods were performed in two healthy volunteers to calculate FV maps for comparison.

Results: Breath-hold UTE method produced FV maps with low contrast in both subjects, while free-breathing UTE method obtained FV maps with good contrast.

Impact: The proposed free-breathing UTE method is straightforward to implement in clinical practice, and can provide satisfactory quantitative FV maps in subjects who fail to maintain breath-hold, improving the success rate of clinical UTE functional lung imaging.

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Keywords