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Abstract #1879

TE-dependent observed lung T1 measured using inversion recovery radial turbo spin echo

Simon Michael Florian Triphan1,2, Ke Zhang1, Hans-Ulrich Kauczor1,2, and Mark Oliver Wielpütz1,2
1Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany, 2Translational Lung Research Center (TLRC), member of the German Center for Lung research (DZL), Heidelberg, Germany

Synopsis

Keywords: Lung, Lung

Motivation: Observed lung T1 from Look-Locker inversion recovery depends on TE due to compartments in the lungs. These differ in T2* and T1, changig visible T1 dependent on TE.

Goal(s): To examine further whether this dependence is due to differences in T2’ or T2.

Approach: Lung T1 was quantified in volunteers using inversion recovery radial TSE at 5 TIs. rTSE was acquired in free breathing using golden angle encoding.

Results: Observed lung T1 was found to increase from T1(5.7ms)=985ms±69ms up to T1=1136±168ms at about TE=57ms and subsequently decreased but with greatly increased spread at longer TEs.

Impact: Observed T1 in the lungs shows a dependence on TE in gradient echo sequences due to different T2* and T1 in tissue compartments. Here, we show TE-dependence due to T2 weighting and thus compartments also differ in T2.

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Keywords