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Abstract #1909

Intracranial Pressure Alterations in different phases of Ménière's Disease: Noninvasive MRI assessment of cerebrospinal fluid pressure

Shuangyuan Zhou1, Jilin Nie2, Xinchen Yu2, and Canglin Yan2
1Radiology, Xiangya Hospital, Central South University, Changsha, China, 2Xiangya Hospital, Central South University, Changsha, China

Synopsis

Keywords: Head & Neck/ENT, Head & Neck/ENT

Motivation: Low cranial pressure can cause Ménière's Disease (MD) symptoms, but this link is unexplored. Traditional cerebrospinal fluid pressure (CSF-P) measurement methods are flawed.

Goal(s): Our study employs a noninvasive MRI technique to assess CSF-P in MD patients, comparing intracranial pressure during acute and remission phases and its correlation with symptoms.

Approach: We used MRI with a fat-suppressed fast recovery fast spin echo (FRFSE) T2-weighted sequence to measure the optic nerve subarachnoid space width (ONSASW) as a CSF-P indicator.

Results: We found that CSF-P in the acute MD group was significantly lower than in the remission or control groups and correlated with hearing thresholds.

Impact: This study first employs noninvasive MRI to measure intracranial pressure in Ménière's Disease (MD), revealing CSF-P reduction and its correlation with hearing thresholds in acute MD. The results could guide clinical treatments like diuretics and provide insights into MD's pathogenesis.

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