Keywords: Adolescents, Adolescents
Motivation: Understanding the pituitary gland role in pre-pubertal growth and adolescent, as abnormalities in hormone levels can cause developmental issues.
Goal(s): This study aimed to measure pituitary volume using the 3D CUBE MRI technique and assess its correlation with serum levels of IGF-1, IGFBP-3, and GH.
Approach: 380 children aged 3-12 underwent serum hormone analysis and MRI scans to quantify adenohypophysis volume and height.
Results: Adenohypophysis volume (aPV) correlates strongly with IGF-1 (r = 0.609) and IGFBP-3 (r = 0.560), while growth hormone (GH) has a weak association (r = 0.083). Age, height, and weight significantly influence these relationships, with no impact from gender.
Impact: This research highlights the 3D CUBE MRI technique's potential to non-invasively assess pituitary morphology and its hormonal associations, providing valuable insights for pediatric endocrinology and enhancing diagnostic strategies while reducing reliance on contrast agents and associated procedural risks.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords