Abstract #2125

Automated assessment of background parenchymal enhancement on breast MRI: Impact on breast cancer risk in a matched cohort study

Heera Yoen¹, Seohyeon Kim², Seon-Ok Kim³, and Su Min Ha¹

¹Radiology, Seoul National University Hospital, Seoul, Korea, Republic of, ²College of Medicine, Seoul National University, Seoul, Korea, Republic of, ³Department of Clinical Epidemology and Biostatistics, University of Ulsan College of Medicine, Seoul, Korea, Republic of

Synopsis

Keywords: Breast, Screening, Background Parenchymal Enhancement

Motivation: Background parenchymal enhancement (BPE) is assessed on contrast-enhanced breast MRI, but its association with breast cancer risk remains unclear.

Goal(s): This study aims to investigate the association between BPE, measured through an automated method, and breast cancer risk.

Approach: We analyzed the effect of BPE on breast cancer risk, balancing for age and menopausal state at the time of MRI examination in patients with and without breast cancer.

Results: The ratio of BPE-to-fat was strongly associated with breast cancer.

Impact: With more robust measurement, BPE alongside with clinical risk factors and breast density could enhance breast cancer risk assessment. This could help optimize breast screening strategy through a multimodal approach.

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