Keywords: Breast, IVIM, vMRE,rMRE
Motivation: Real magnetic resonance elastography (rMRE) assesses breast tissue stiffness but has limited accessibility due to hardware demands and patient tolerance issues. IVIM-based virtual MR elastography (vMRE) could offer a feasible alternative.
Goal(s): This study evaluates whether vMRE can differentiate normal, benign, and malignant breast lesions, potentially replacing rMRE in clinical use.
Approach: In 21 patients with breast lesions and 5 healthy controls, diagnostic performance was assessed with rMRE and vMRE, optimizing b-value combinations for virtual shear-wave speed (Cv-MRE).
Results: The optimal b-value pair (200 and 1500 sec/mm2 )enabled Cv-MRE to distinguish malignant from benign lesions, achieving high diagnostic accuracy (AUC=0.929) .
Impact: IVIM-based vMRE shows potential as a non-invasive alternative to rMRE for breast lesion diagnosis, offering broader applicability in patient care by enhancing diagnostic accessibility, especially for cases unsuited to traditional rMRE.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords