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Abstract #2140

Evaluation of 23Na signals in gynecological malignancies using 23Na MRI

Tsukasa Saida1, Miki Yoshida2, Yuta Nakahashi2, Masashi Shindo3, Koji Yamada3, Takao Ishimori 3, Jihun Kwon4, and Takahito Nakajima1
1Diagnostic and Interventional Radiology, University of Tsukuba, Tsukuba, Japan, 2Diagnostic and Interventional Radiology, University of Tsukuba Hospital, Tsukuba, Japan, 3Radiology, University of Tsukuba Hospital, Tsukuba, Japan, 4MR Clinical Science, Philips Japan, Ltd, Tokyo, Japan

Synopsis

Keywords: Uterus, Non-Proton, ovary

Motivation: Advances in sodium (23Na) MRI technology enable non-invasive evaluation of tumor physiology by measuring tissue sodium concentrations.

Goal(s): This study aimed to assess 23Na signals in endometrial and ovarian cancers to explore their potential clinical utility.

Approach: Phantom experiments evaluated coil sensitivity and signal attenuation, while clinical assessments measured 23Na signals in cancerous and normal tissues to facilitate comparisons.

Results: 23Na signals were significantly higher in malignant tissues, with ovarian cancer showing the highest intensities.

Impact: 23Na MRI holds potential to differentiate benign from malignant lesions, improving diagnostic accuracy and understanding of disease pathophysiology.

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Keywords