Keywords: Diffusion Analysis & Visualization, Breast
Motivation: Oscillating gradient diffusion-weighted imaging (OG-DWI) offers advanced microstructural insights, capturing cell density, diameter, and intracellular volume fraction, metrics often inaccessible with conventional MRI.
Goal(s): This study aimed to evaluate OG-DWI’s utility in quantitatively distinguishing breast lesions.
Approach: Using OG-DWI, we effectively differentiated benign from malignant lesions, particularly at lower ADC percentiles.
Results: These results suggest OG-DWI as a promising noninvasive imaging biomarker, enabling more accurate assessment of breast cancer aggressiveness by highlighting subtle microstructural differences linked to malignancy, thus enhancing diagnostic specificity.
Impact: Oscillating gradient DWI, with shorter diffusion times, complements conventional pulsed gradient DWI by revealing additional tumor microstructural details. Combined OGSE and PGSE sequences may enable novel diffusion-based biomarkers for improved breast lesion characterization and stratification.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords