Keywords: Perfusion, Quantitative Imaging, in vivo Blood T1; ultrafast Imaging; inversion recovery
Motivation: Blood T1 measurement could be accelerated to a single-shot with Golden Angle rotated Spiral k-t Sparse Parallel imaging (GASSP), by exploiting temporal sparsity from the images acquired at successive inversion delays.
Goal(s): This work aimed to apply GASSP to reduce measurement time from 60s with 6-shot to 10s with single-shot at 1mm2 in-plane resolution.
Approach: On 9 healthy volunteers, GASSP was compared to the traditional EPI readout, and was repeated to assess its intra-scan reproducibility.
Results: Blood T1 values measured with highly undersampled GASSP was strongly correlated with traditional EPI readout and exhibited high reproducibility.
Impact: This study showed that the ultrafast (~10s) blood T1 measurement at the internal jugular vein with 1mm2 in-plane resolution using Golden Angle rotated Spiral k-t Sparse Parallel imaging (GASSP) yielded comparable performance with EPI and high intra-scan reproducibility.
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