Keywords: Motion Correction, Brain, Laminar (f)MRI
Motivation: Classical 1D linescan acquisitions have recently been shown to be valuable for recording in-vivo MRI signals across the layers of human cerebral cortex; however, these reduced-field-of-view techniques are vulnerable to rotational head movements as well as translations parallel and perpendicular to the line.
Goal(s): To acquire high-quality, high-resolution linescan data that is robust to "in-line" and "through-line" motion.
Approach: 3D-EPI volumetric navigators (vNavs) were incorporated into a spin-echo-based linescan pulse sequence.
Results: We demonstrate that, by combining prospective and retrospective motion correction, we can acquire reliable linescan data with 0.5-mm readout resolution at 7T, in the presence of in-line and through-line head motion.
Impact: Motion-robust linescan techniques will help enable the measurement of tissue microstructure and microvascular fMRI signals at high spatial resolutions, approaching the thickness of individual cortical layers, facilitating noninvasive studies of cortical circuitry and architectonics in the living human brain.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords