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Abstract #2364

Evaluation of Middle Cerebral Artery Vessel Wall in Anterior Circulation Transient Ischemic Attack: A 5.0 T MRI and 3D High-Resolution Study

Liang Yin1, jing wang1, ZongChang Li1, dan yu2, and jie gan1
1Shandong Provincial Third Hospital, Jinan, China, 2United Imaging Research Institute of Intelligent Imaging, Beijing, China

Synopsis

Keywords: Stroke, High-Field MRI

Motivation: TIAs are warning signs for ischemic strokes, but early detection of high-risk vascular changes is challenging. Identifying vessel wall abnormalities in the MCA could improve risk assessment and prevention.

Goal(s): To determine whether 5.0 T MRI with 3D high-resolution VWI enhances detection of MCA wall abnormalities in patients with anterior circulation TIAs.

Approach: Used 5.0 T MRI with 3D-VWI to measure MCA wall thickness, cross-sectional area, and eccentricity in TIA patients and age-matched healthy controls.

Results: TIA patients showed significantly greater MCA wall thickness, larger cross-sectional areas, and more frequent eccentric wall thickening than controls, indicating effective detection of high-risk vascular changes.

Impact: This study demonstrates that 5.0 T MRI with high-resolution 3D-VWI can reliably identify high-risk structural changes in TIA patients, enhancing early stroke risk assessment and potentially guiding personalized intervention strategies for improved patient outcomes.

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