Meeting Banner
Abstract #2374

Field-Cycling imaging detects brain tumours at low magnetic field strengths

Vasiliki Mallikourti1, James Peter Ross1, Gareth Davies1, Hana Lahrech2, David Lurie1, Lionel Marc Broche3, and Arnab Rana4
1Biomedical Physics, University of Aberdeen, Aberdeen, United Kingdom, 2BrainTech Lab, Université Grenoble Alpes, Grenoble, France, 3Centre for Adaptable Technologies, University of Aberdeen, Aberdeen, United Kingdom, 4Radiology Department, Aberdeen Royal Infirmary, Aberdeen, United Kingdom

Synopsis

Keywords: Tumors (Pre-Treatment), Cancer

Motivation: Field Cycling Imaging (FCI) is a new imaging modality that shows high potential in brain glioma from ex-vivo studies.

Goal(s): Our goal was to demonstrate the capabilities of FCI as an imaging modality to detect brain cancer in vivo.

Approach: Nine patients were imaged with our recent FCI prototype scanner using fields from 0.2 to 200mT. T1 images were compared with standard 1.5T MRI clinical images.

Results: Tissue contrast appeared between tumours and uninvolved tissues that agreed with ex-vivo results, showing biomarkers of aquaporins activity. This discriminated gliomas from peritumoural regions, as well as gliomas from meningiomas.

Impact: FCI can detect brain tumour and discriminates glioma from meningioma. Tissue dispersion may also be a marker of aggressiveness. These offer interesting prospects for clinical applications.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords