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Abstract #2376

T2 mapping for evaluating consistency of pituitary macroadenomas: a preliminary study

Chun-Qiu Su1, Yi-Cheng Hsu2, Tobias Kober3, and Shan-Shan Lu1
1The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2MR Collaboration, Siemens Healthcare Ltd., Shanghai, China, 3Advanced Clinical Imaging Technology, Siemens Suisse SA —CIBM, Lausanne, Switzerland

Synopsis

Keywords: Tumors (Pre-Treatment), Neuro

Motivation: Preoperative evaluation of pituitary adenoma (PA) consistency is crucial for surgical strategy, but previous studies using conventional T2-weighted imaging (T2WI) have yielded controversial results regarding their ability to assess tumor consistency.

Goal(s): To evaluate the ability of the T2-mapping to predict the consistency of PAs.

Approach: We conducted accelerated T2 mapping on 25 patients with PAs, analyzing T2 relaxation times and comparing T2 values between soft and hard tumors.

Results: T2 mapping showed a significant difference in T2 relaxation times between hard and soft PAs (P=0.005), while T2WI showed no significant difference (P=0.440), indicating that T2 mapping provides valuable information about tumor consistency.

Impact: Accelerated T2 mapping provides a reliable, noninvasive method to predict pituitary adenoma consistency preoperatively, outperforming T2W imaging. This enhances surgical planning and potentially improves patient outcomes through more accurate assessment of tumor characteristics within a feasible clinical workflow.

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