Keywords: Tumors (Post-Treatment), MR Value, cerebrospinal fluid pressure；non⁃small cell lung cancer；leptomeningeal metastasis；optic nerve sheath diameter
Motivation: Patients with NSCLC brain matastasis usually have elevated CSF pressure
Goal(s): To assess the diagnostic accuracy of combined ONSD and PCSFV/ICV in diagnosing elevated CSFP.
Approach: Both optic nerve and cranial MR scans were performed to measure bilateral ONSD，cranial PCSFV and ICV. Subsequently，CSFP was measured in all patients through lumbar puncture.
Results: The average ONSD of bilateral eyes was positively correlated with CSFP（r=0.567，P < 0.001）. PCSFV/ICV was negatively correlated with CSFP（r=-0.365，P=0.003）.
Impact: The utilization of MR for measuring ONSD and PCSFV/ICV provides a valuable means to assess variations in CSFP among patients diagnosed with NSCLC⁃LM.
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