Keywords: Normal Development, Diagnosis/Prediction, adenohypophyseal volume, adenohypophysis height, hypothalamic-pituitary-gonadal axis, central precocious puberty
Motivation: Evaluation of HPG axis activation among patients with PP or CPP is essential for treatment decisions.
Goal(s): To assess the potential diagnostic value of adenohypophysis volume (aPV).
Approach: A cohort of 593 children was included. Partial correlation analysis was conducted to examine the associations between aPV and aPH with LH peak and LH/FSH ratio. Multiple linear regression equations were constructed, and diagnostic performance was evaluated by ROC analysis and ICC analysis.
Results: This study obtained accurate pituitary volume and established predictive models for LH and LH/FSH. The study confirmed that pituitary volume better reflects the status of gonadal axis initiation.
Impact: aPV and aPH demonstrated potential diagnostic value in assessing HPG-axis initiation status. The multiple linear regression equations incorporating age, weight and adenohypophysis volume showed promise for predicting LH peak and LH/FSH ratio, providing insights into non-invasive methods for assessing precocity.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords