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Abstract #2432

Preliminary exploration of the value of 5T MRI arterial spin labeling and morphological indexes in staging chronic kidney disease

Ting Rong1, Junfeng Kong2, Wenbing Zeng2, Shaoxin Xiang 3, and Zhichao Feng4
1School of Medical Imaging,North Sichuan Medical College, Nanchong City, Sichuan Province, China, 2Three Gorges Hospital affiliated to Chongqing University, Chongqing, China, 3United Imaging Research Institute of Intelligent Imaging, Beijing, China, 4Central Research Institute, United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Kidney, fMRI Analysis, Chronic kidney disease; Arterial spin labeling; Magnetic resonance imaging, ultra-high-field 5T; Morphological indexes

Motivation: The 5T ultra-high-field MRI could offers high-resolution structural and functional imaging of the kidneys. However, its potential in distinguishing different stages of Chronic kidney disease remains unclear.

Goal(s): To explore the value of 5T ASL magnetic resonance imaging and morphological indexes for staging chronic kidney disease.

Approach: Prospective analysis of renal blood flow and morphological differences in 95 patients with stage 1-5 of CKD.

Results: The morphological indicators and quantitative parameters of ASL allow effective assessment and differentiation across 5 different stages of CKD.

Impact: In conclusion, the synergistic application of ASL and morphological assessment utilizing 5T MRI facilitates a noninvasive, precise, and comprehensive functional and morphological evaluation, which is pivotal for the clinical staging of CKD.

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Keywords