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Abstract #2522

Vessel wall imaging of vertebrobasilar artery configurations: associations with posterior circulation infarction in atherosclerosis

Jingtong Xiong1,2, Lingjung Mei2, Chen Zhang3, Xiaofeng Qu2, and Jianlin Wu1,4
1Graduate School, Tianjin Medical University, Tianjin, China, 2Radiology, The Second Hospital of Dalian Medical University, Dalian, China, 3MR Research Collaboration, Siemens Healthineers, Beijing, China, 4Radiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China

Synopsis

Keywords: Stroke, Stroke

Motivation: Vertebrobasilar artery (VBA) configurations have been reported to affect vessel hemodynamics of posterior circulation. High-resolution MR vessel wall imaging (VWI) offers the dual advantages of observing vascular morphology and evaluating high-risk plaques.

Goal(s): Our study sought to determine whether certain VBA morphological characteristics are associated with an increased risk of posterior circulation infarction (PCI) using VWI.

Approach: A retrospective case–control study of 249 participants (98 PCIs and 151 non-PCIs).

Results: Percentages of PCI patients was higher in walking and lambda configurations than that in tuning fork. Mean diameter of bi-VAs and grade of BA lateral position were independent risk factors associated with PCI.

Impact: Finding of this study will contribute to the stratification of stroke risk and significantly impact on clinical guidelines and treatment protocols for stroke prevention and management. Ultimately, this will be a step towards accurate diagnosis and treatment of PCI.

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