Keywords: Stroke, Stroke
Motivation: Vertebrobasilar artery (VBA) configurations have been reported to affect vessel hemodynamics of posterior circulation. High-resolution MR vessel wall imaging (VWI) offers the dual advantages of observing vascular morphology and evaluating high-risk plaques.
Goal(s): Our study sought to determine whether certain VBA morphological characteristics are associated with an increased risk of posterior circulation infarction (PCI) using VWI.
Approach: A retrospective case–control study of 249 participants (98 PCIs and 151 non-PCIs).
Results: Percentages of PCI patients was higher in walking and lambda configurations than that in tuning fork. Mean diameter of bi-VAs and grade of BA lateral position were independent risk factors associated with PCI.
Impact: Finding of this study will contribute to the stratification of stroke risk and significantly impact on clinical guidelines and treatment protocols for stroke prevention and management. Ultimately, this will be a step towards accurate diagnosis and treatment of PCI.
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