Keywords: Tumors (Post-Treatment), DWI/DTI/DKI, Pituitary adenomas, GRASP-DCE, SMS-RESOLVE DW, subjective andobjective evaluations, pharmacokinetic analysis
Motivation: Postoperative evaluation of pituitary neuroendocrine tumors (PitNETs) is challenging, as conventional contrast-enhanced MRI struggles to differentiate residual tumor tissue from surgical changes.
Goal(s): This study aimed to evaluate the effectiveness of GRASP DCE-MRI and SMS-RESOLVE DWI in detecting and characterizing residual PitNETs, emphasizing sensitivity and quantitative analysis.
Approach: In a prospective study of 30 postoperative PitNET patients, two radiologists independently analyzed images, with quantitative perfusion analysis performed using the Tofts model.
Results: GRASP DCE-MRI detected residual tumors as small as 0.2 cm with high accuracy, while SMS-RESOLVE matched CE-T1WI’s diagnostic performance for tumors ≥0.9 cm without contrast agents.
Impact: This study highlights GRASP DCE-MRI and SMS-RESOLVE DWI as advanced tools that improve the detection and monitoring of postoperative residual PitNETs, providing reliable non-contrast imaging options and potentially guiding improved clinical decision-making.
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