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Abstract #2669

Novel multi-parameter MRI-based MPET1 Model for Identification of Metabolic dysfunction-associated steatohepatitis

Wenxin Ma1, Xutong Huang1, Yuejun Sun1, Zhiwei Qin2, Wenli Tan1, and Jie Yuan1
1Imaging medicine, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shang Hai, China, 2MR Collaboration, United Imaging Research, Shang Hai, China

Synopsis

Keywords: Liver, biology, models, methods

Motivation: Non-invasive identification of Metabolic dysfunction-associated steatohepatitis (MASH) are essential.Due to the limitations of existing non-invasive models, it is necessary to explore a more accurate identification model.

Goal(s): To explore a novel model based on multi-parameter MRI indicators in the identification of MASH.

Approach: Of the 84 patients who met the study requirements, 68 were diagnosed with MASH. The SPSS Statistics software was used to construct the model.

Results: MEPT1 model constructed by MRE, PDFF and T1mapping was the best identification model with satisfactory fitting and high identification performance and recognition ability (AUC 0.899).

Impact: The MEPT1 model based on multi-parameter MRI is more accurate and superior to MAST score in noninvasive identification of MASH patients, which can assist clinical identification and evaluation of MASH patients.

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