Keywords: Pancreas, Pancreas, Chemical exchange saturation transfer
Motivation: It is not known whether APT imaging is useful for the pancreas. In addition, the pancreas can be affected by the presence of fat deposition.
Goal(s): To verify whether APT-Dixon can be used for the pancreas, and to verify the differences between APT-TSE and APT-Dixon sequences.
Approach: APT-TSE and APT-Dixon sequences were compared for PDAC and the pancreatic parenchyma. APT signals within PDAC and pancreatic parenchyma were compared between APT-TSE and APT-Dixon sequences.
Results: APT-Dixon showed a significantly higher signal compared to APT-TSE in PDAC and the pancreatic parenchyma. PDAC showed a lower APT signal compared to the pancreatic parenchyma with APT-Dixon.
Impact: Pancreatic APT signal in APT-TSE is affected by the presence of fat deposition. Therefore, APT-Dixon is essential for analysis of the pancreatic APT signal. APT imaging in the pancreas may have the potential to assess the biological behaviour of PDAC.
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