Keywords: Kidney, Tumors, multiparametric
Motivation: Dynamic contrast-enhanced MRI (DCE-MRI) offers a non-invasive method to assess perfusion in solid renal masses (SRM), potentially aiding in their characterization.
Goal(s): This study evaluated the diagnostic performance of modeled and model-free DCE-MRI parameters for differentiating SRM subtypes.
Approach: In a prospective, single-center study of 43 patients with SRMs, we assessed the performance of 26 modeled/model-free DCE-MRI parameters for SRM subtyping.
Results: Model-free parameters demonstrated significant differences between malignant and benign SRMs, while modeled parameters did not. Multiparametric models incorporating ccLS demonstrated identified malignant vs benign, ccRCC vs. non-ccRCC vs and ccRCC vs other SRM with good diagnostic performance.
Impact: Model-free parameters demonstrated significant differences between malignant and benign SRMs, while modeled parameters did not. Multiparametric models incorporating ccLS demonstrated identified malignant vs benign, ccRCC vs. non-ccRCC vs and ccRCC vs other SRM with good diagnostic performance.
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