Meeting Banner
Abstract #2691

Modeled and Model-Free DCE-MRI Parameters to Identify Solid Renal Mass Subtype in Patients Undergoing Surgical Management

Xin Mu1, Mira Liu1, Haitham Al-Mubarak2, Paul Kennedy1, Philip Robson1, Jordan Cuevas1, Bernd Kuhn3, Ketan Badani4, Bachir Taouli1,5, Sara Lewis1, and Octavia Bane1,6
1Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Siemens Healthcare, Erlangen, Germany, 4Urology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 5BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 6BioMedical Engineering and Imaging Institute, Mount Sinai Hospital, New York, NY, United States

Synopsis

Keywords: Kidney, Tumors, multiparametric

Motivation: Dynamic contrast-enhanced MRI (DCE-MRI) offers a non-invasive method to assess perfusion in solid renal masses (SRM), potentially aiding in their characterization.

Goal(s): This study evaluated the diagnostic performance of modeled and model-free DCE-MRI parameters for differentiating SRM subtypes.

Approach: In a prospective, single-center study of 43 patients with SRMs, we assessed the performance of 26 modeled/model-free DCE-MRI parameters for SRM subtyping.

Results: Model-free parameters demonstrated significant differences between malignant and benign SRMs, while modeled parameters did not. Multiparametric models incorporating ccLS demonstrated identified malignant vs benign, ccRCC vs. non-ccRCC vs and ccRCC vs other SRM with good diagnostic performance.

Impact: Model-free parameters demonstrated significant differences between malignant and benign SRMs, while modeled parameters did not. Multiparametric models incorporating ccLS demonstrated identified malignant vs benign, ccRCC vs. non-ccRCC vs and ccRCC vs other SRM with good diagnostic performance.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords