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Abstract #2703

Free-breathing abdominal CEST imaging at 3T with a steady-state MultiVane MRI acquisition

Siyuan Ma1, Fulong Song1, Zhouyan Liao1, Pan Luo1, Qiuxia Wang1, Xiaoxiao Zhang2, Ning Zheng2, Gen Chen1, and Zhen Li1
1Department of Radiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2MSC Clinical & Technical Solutions, Philips Healthcare, Beijing, China

Synopsis

Keywords: fMRI Acquisition, Data Acquisition

Motivation: This study is motivated by the need to overcome the limitations of abdominal chemical exchange saturation transfer (CEST) imaging, which is highly affected by motion, limiting its clinical utility for liver and kidney assessments.

Goal(s): The goal is to develop a free-breathing CEST imaging sequence that maintains high image quality and acquisition efficiency without requiring patient breath-holding.

Approach: A steady-state MultiVane MRI technique was implemented, enabling radial acquisition that corrects in-plane motion, enhancing image stability and quality.

Results: The new free-breathing sequence achieved homogeneous, high-quality CEST images of the liver and kidneys, demonstrating potential for broader clinical and research applications.

Impact: This study facilitates non-invasive, motion-corrected free-breathing CEST imaging, enhancing abdominal imaging for liver and kidney diagnostics. By eliminating breath-hold limitations, it supports broader metabolic studies, potentially advancing clinical applications and enabling new research into disease biomarkers and molecular changes.

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