Keywords: fMRI Analysis, Treatment, arterial spin labeling, voxel-based morphometry, migraine, patent foramen ovale, patent foramen ovale closure
Motivation: Assessing effects of PFO closure on CBF and GMV in migraineurs with PFO via multimodal MRI.
Goal(s): Using multimodal MRI to evaluate resting-state CBF and GMV changes in migraineurs with PFO, pre- and post-closure, providing neuroimaging insights on PFO closure's efficacy for migraine.
Approach: Baseline and post-treatment pcASL and high-res T1WI images were acquired from migraineurs with PFO and healthy controls. Using ASL post-processing and VBM, standardized preprocessing and statistical modeling analyzed interictal resting-state CBF and GMV differences pre- and post-PFO closure in migraineurs.
Results: Migraineurs with PFO show pre- and post-treatment abnormalities in CBF and GMV across multiple brain regions.
Impact: Resting-state pcASL and VBM aid in exploring neuroimaging mechanisms of headache relief in migraineurs with PFO post-PFO closure.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords