Abstract #2739

Multi-Scanner Repeatability and Reproducibility of quadratic RF phase MRF Breath-held and Free-breathing with Pilot Tone

Madison E. Kretzler¹, Eduardo Thadeu de Oliveira Correia^2,3, Jessie E.P. Sun¹, Chris A. Flask¹, Mark A. Griswold¹, and Rasim Boyacioglu⁴

¹Radiology, Case Western Reserve University, Cleveland, OH, United States, ²Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States, ³School of Medicine, Case Western Reserve University, Cleveland, OH, United States, ⁴Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: MR Fingerprinting, MR Fingerprinting, Repeatability, Reproducibility, Free-Breathing, Quantitative Imaging

Motivation: Ensuring independent agreement using breath-hold (BH) and free-breathing with Pilot Tone (PT) quadratic RF phase Magnetic Resonance Fingerprinting (qRF-MRF) in abdomen.

Goal(s): Show repeatability and reproducibility of T1, T2, and T2* maps generated using BH and free-breathing with PT qRF-MRF.

Approach: qRF-MRF scan-rescan of 2D-axial abdominal slices performed across two same-site Siemens 3T scanners. Reconstructions analyzed through liver ROIs and compared in Bland-Altman plots for repeatability and reproducibility.

Results: Bland-Altman results show good agreement, low bias for resulting reconstructed BH and PT qRF-MRF T1, T2, and T2* results between inter- and intra-scanner results and between BH and PT scans.

Impact: The independence of qRF-MRF fidelity, despite repeat scans or different scanner usage, is important for adopting into a clinical workflow. This study demonstrates this through the repeatability and reproducibility of breath-hold qRF-MRF and free-breathing qRF-MRF with pilot tone (PT).

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.