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Abstract #2762

In vivo R2* and QSM on the 11.7T whole-body Iseult MRI System using Universal Pulses Transmission and Virtual Coil Reconstruction

Mathieu David Santin1, Mélanie Didier1, Franck Mauconduit2, Aurélien Massire3, Caroline Le Ster2, Romain Valabregue1, Vincent Gras2, Michel Luong2, Alexis Amadon2, Michel Bottlaender2, Nicolas Boulant2, and Alexandre Vignaud2
1Center For NeuroImaging Research (CENIR), Paris Brain Institute - ICM, Paris, France, 2Neurospin, CEA, Gif-sur-Yvette, France, 3Siemens Healthineers, Courbevoie, France

Synopsis

Keywords: Quantitative Imaging, Quantitative Susceptibility mapping, Ultra-High Field, Iseult, R2*, Human 11.7T, QSM, pTx

Motivation: Our motivation was to produce susceptibility and R2* maps in a cohort of healthy subjects

Goal(s): Obtain normative values of R2* and QSM in the basal ganglia of healthy subjects at 11.7T

Approach: Combination of Ultra-high Field (11.7T), Universal Pulses for RF transmission, Virtual Coil approach for complex magnitude and phase image generation, state-of-the-art susceptibility mapping techniques and deep learning for image segmentation.

Results: Normative values were obtained for R2* and susceptibility values in the basal ganglia of healthy subjects.

Impact: This study paves the way for the use of QSM and R2* at ultra-high field (11.7T)

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Keywords