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Abstract #2795

Value of two-point Dixon fat-corrected Look-Locker T1 mapping on the assessment of liver fibrosis in chronic liver disease with hepatic steatosis

Mayumi Higashi1, Masahiro Tanabe1, Ute Goerke2, Hiroshi Imai3, and Katsuyoshi Ito1
1Department of Radiology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan, 2Siemens Healthcare USA, Tucson, AZ, United States, 3MR Research and Collaboration, Siemens Healthcare K.K, Tokyo, Japan

Synopsis

Keywords: Liver, Fat and Fat/Water Separation

Motivation: Recently emerging two-point Dixon fat-corrected Look-Locker T1 mapping of the liver is developed as a new imaging technique that can measure the T1 value without the impact of fat.

Goal(s): To evaluate how the presence of fat affects the assessment of liver fibrosis in patients with chronic liver disease using two-point Dixon fat-corrected Look-Locker T1 mapping.

Approach: T1 values of liver were compared between T1 maps obtained by fat-uncorrected and fat-corrected sequences.

Results: Assessment of liver fibrosis in chronic liver disease by fat-corrected T1 mapping was less influenced by the presence of fat.

Impact: 2D two-point Dixon fat-corrected Look-Locker T1 mapping is essential for the proper assessment of liver fibrosis in patients with chronic liver disease under the presence of substantial hepatic steatosis.

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