Keywords: Liver, Fat and Fat/Water Separation
Motivation: Recently emerging two-point Dixon fat-corrected Look-Locker T1 mapping of the liver is developed as a new imaging technique that can measure the T1 value without the impact of fat.
Goal(s): To evaluate how the presence of fat affects the assessment of liver fibrosis in patients with chronic liver disease using two-point Dixon fat-corrected Look-Locker T1 mapping.
Approach: T1 values of liver were compared between T1 maps obtained by fat-uncorrected and fat-corrected sequences.
Results: Assessment of liver fibrosis in chronic liver disease by fat-corrected T1 mapping was less influenced by the presence of fat.
Impact: 2D two-point Dixon fat-corrected Look-Locker T1 mapping is essential for the proper assessment of liver fibrosis in patients with chronic liver disease under the presence of substantial hepatic steatosis.
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