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Abstract #2798

Comparing Gastrointestinal (GI) Motility scoring using Cine T2-weighted bSSFP and SSFSE Sequences in MR Enterography

Elima Hussain1, Andreas M. Loening1, Richa Patel1, Iyad Naim2, Ali B. Syed1, and Vipul R. Sheth1
1Department of Radiology, Stanford University, Stanford, CA, United States, 2Motilent Ltd., London, United Kingdom

Synopsis

Keywords: Digestive, Analysis/Processing, Gastrointestinal Motility, MRI Enterography, SSFP (Steady-State Free Precession), SSFSE (Single-Shot Fast Spin Echo)

Motivation: GI motility, a biomarker for acute inflammation in inflammatory bowel disease in MR enterography 1,2(MRE), has been quantified with cine bSSFP sequences, and not with the SSFSE sequences.

Goal(s): Assess how different types of dynamic sequences may change the measured motility score in normal appearing bowel.

Approach: We compared the GI Quant motility scores in cine bSSFP to a cine SSFSE sequence in 31 patients.

Results: GI Quant score is significantly different between the two techniques with a numerically higher score in SSFSE likely due to its longer time interval between frames.

Impact: A correction factor may be required for use of SSFSE sequences for dynamic small bowel motility assessment with GI Quant. Motility is a biomarker of inflammation in patients with inflammatory bowel disease.

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Keywords