Abstract #2808

MRI-guided PET reconstruction with adaptive prior strength of renal masses

Chunwei Ying¹, Junyu Guo², Mahsa Taherzadeh², Clive Musonza², Robert C. Sibley², Farzad Tahmasebi Arashloo², Jorge Cabello³, Qing Yuan², David Faul⁴, and Ivan Pedrosa²

¹Siemens Medical Solutions USA Inc., Dallas, TX, United States, ²UT Southwestern Medical Center, Dallas, TX, United States, ³Siemens Medical Solutions USA Inc., Knoxville, TN, United States, ⁴Siemens Medical Solutions USA Inc., New York, NY, United States

Synopsis

Keywords: Kidney, Kidney, PET/MR; MRI-guided PET reconstruction; renal masses

Motivation: A method for MRI-guided PET reconstruction with adaptive prior strength was developed to improve PET image quality. This study aims to evaluate its effect on renal mass identification.

Goal(s): Evaluate the impact of MRI-guided PET reconstruction on renal mass identification.

Approach: The renal mass ROI was defined on HASTE MRI. SUV_max and SUV_mean were obtained in the lesion ROIs.

Results: MRI-guided PET reconstruction improves PET image quality and allows for better visual delineation of renal masses from the background. In the renal mass ROI, SUV_max decreases slightly with a higher MRI prior influence level, while SUV_mean does not change.

Impact: MRI-guided PET reconstruction improves PET image quality using high-resolution and high soft-tissue contrast MRI as prior. Our preliminary results demonstrate the feasibility of MRI-guided PET reconstruction in patients with renal mass.

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