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Abstract #2817

Uro-Dynamic MRI Reveals Biphasic Behavior of the Bladder During Voiding

Juan Pablo Gonzalez-Pereira1,2, Evan Turner1,2, Helen Sargeant3, Matthew Grimes4, Wade Bushman4, and Alejandro Roldan-Alzate1,2,3
1Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 2Radiology, University of Wisconsin-Madison, Madison, WI, United States, 3Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 4Urology, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Urogenital, Bladder, Biomechanics, Biphasic, Sphericity Index

Motivation: Current standards for the lower urinary tract (LUT) assessment provide limited anatomical information. Uro-Dynamic MRI non-invasively characterized bladder behavior as a non-linear event. Anatomical measurements (AM) describing bladder shape could be linked to urinary flow rate during voiding.

Goal(s): Describe bladder behavior during voiding by linking anatomical changes and urinary flow rate.

Approach: Uro-Dynamic MRI was implemented in 10 subjects. AM were quantified for each subject.

Results: Sphericity index reveals biphasic behavior of bladder during voiding. Correlation coefficients between AM and urinary flow rate are higher when analyzing voiding event as a biphasic event rather than a single-phase event.

Impact: Uro-Dynamic MRI reveals a biphasic behavior of bladder during voiding as measured by sphericity index. Correlation coefficients between anatomical measurements and urinary flow rates are higher when analyzing the voiding event as a biphasic event than as a singular event.

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Keywords