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Abstract #2896

Diagnostic value of synthetic MRI combined with MUSE-DWI in cystic solid tumors of the ovary

CHENG HUI1, TANG WEN WEI1, TIAN ZHONG FU1, LU XIAO YAN1, YAO XIAO YAO1, ZHANG JIN QI1, and Dmytro Pylypenko2
1Women's Hospital Of Nanjing Medical University, Nanjing, China, 2GE Healthcare, MR Research, Beijing, China

Synopsis

Keywords: Urogenital, Diagnosis/Prediction

Motivation: Accurate differentiation of ovarian cystic-solid tumors is essential for effective treatment, but distinguishing malignant from nonmalignant tumors remains challenging.

Goal(s): To evaluate a combined diagnostic model using MAGiC, MUSE-DWI quantitative parameters, and morphological features for identifying ovarian cystic-solid tumors.

Approach: The study analyzed solid tumor length, O-RADS score, and ADC-MUSE values between malignant and nonmalignant groups, incorporating MUSE-DWI and synthetic PD to improve accuracy.

Results: MUSE-DWI showed strong efficacy in distinguishing tumor types, with synthetic PD reducing false positives. Combining morphological indices with MUSE-DWI further enhanced diagnostic differentiation.

Impact: This study demonstrates that combining synthetic MRI, MUSE-DWI parameters, and morphological features significantly improves diagnostic accuracy for ovarian cystic-solid tumors, offering a valuable tool to distinguish malignant from nonmalignant lesions, potentially reducing misdiagnosis and improving patient outcomes.

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