Keywords: Deuterium, Deuterium
Motivation: Bladder cancer is a common malignant tumor with a high recurrence rate. Metabolic imaging may be an effective method for accurate diagnosis, especially deuterium MRI, which overcomes the shortcoming of bladder tumor signals masked by urine in PET.
Goal(s): To characterize the metabolism of bladder cancer using deuterium MRI.
Approach: Mice model of subcutaneous bladder cancer was established for deuterium MRI.
Results: The “warburg effect” of bladder tumors can be visualized by deuterium MRI, as shown by increased 2H-glucose uptake and 2H-lactate and 2H-water production.
Impact: Our study established that deuterium MRI holds promise to depict the metabolism of bladder cancer. Deuterium MRI is a safe, non-radioactive, and effective imaging modality to diagnosis bladder cancer and guide clinical treatment in the future.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords