Meeting Banner
Abstract #2940

A dual density rosette trajectory for rapid MRSI of the brain with a simultaneously acquired high-resolution anatomical reference

Emile Kadalie1, Lubna Burki1,2, Kaito Hara-Lee1,3, and Jamie Near1,2
1Physical Sciences Research Platform, Sunnybrook Research Institute, Toronto, ON, Canada, 2Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 3Queen's University, Kingston, ON, Canada

Synopsis

Keywords: Spectroscopy, Spectroscopy, MRSI; Rosette; Lipid Suppression

Motivation: MRSI enables mapping of metabolite concentrations throughout the human brain. It is however limited by the contamination of brain spectra due to lipids originating in extracranial adipose tissue.

Goal(s): Our goal was to acquire MRSI data with lipid suppressed spectra in the entire brain with a single sequence and the use of spatial priors.

Approach: A dual-density k-space trajectory was implemented, enabling the acquisition of a high-resolution spatial prior that was used to remove the lipid contamination from the data, without lengthening the scan time.

Results: The resulting MRSI data displayed notable lipid suppression, resulting in metabolite peaks being much more discernible.

Impact: A novel acquisition method was developed to simultaneously collect MRSI data and high-resolution spatial priors to suppress spectral lipid contamination. This technique thus has the potential to become a robust clinical tool for studying metabolic changes in the brain.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords