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Abstract #2965

Semi-Automated Bone Tracking for Dynamic MRI Analysis of Knee Joint Kinematics

Aayush Nepal1, Nicholas M. Brisson2, Georg N Duda2, Felix Güttler3, Jürgen R Reichenbach1, and Martin Krämer1,3
1Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, 2Julius Wolff Institute, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany

Synopsis

Keywords: Functional/Dynamic, Bone, Segmentation, Knee, Kinematics

Motivation: The ability to analyze tibiofemoral kinematics during dynamic imaging is important for research and clinical assessment.

Goal(s): To develop and validate a semi-automated pipeline to track tibiofemoral motion and extract kinematic parameters from sagittal plane CINE MRI.

Approach: A combination of edge detection with connected-component labeling and frame-to-frame transformation optimization was used to track bone boundaries during knee flexion-extension cycles during dynamic MRI. The method was validated in five healthy volunteers and compared with manual segmentation.

Results: Measured kinematics (flexion-extension range of motion: 24.1°±7.2°, anterior-posterior displacement: -18.8±3.2 mm, superior-inferior displacement: 0.8±1.3 mm) matched expected physiological ranges and showed higher accuracy than manual segmentation.

Impact: Direct analysis of dynamic MRI frames can achieve accurate motion tracking of the tibia and femur without requiring high-resolution reference scans. This approach outperforms manual segmentation and streamlines the study of in vivo knee kinematics from imaging data.

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