Abstract #2966

Correlation between functional impairment and quantitative MRI assessment of ankle cartilage in chronic ankle instability.

Rong Lu¹, Zichun Liu², Shanshan Zheng³, Xiao’ao Xue², Ying-Hua Chu⁴, Yuwen Zhang⁵, Tian Xia², Yushi Chen², Zikun Wang², Ziyuan Wang², Shangxuan Shi⁶, Tingfang Hwang¹, Yang Song⁴, Weijun Tang¹, Shuang Chen¹, Yinghui Hua², and He Wang^7,8,9

¹Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China, ²Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China, ³Department of Sports Medicine, School of Exercise and Health, Shanghai University of Sport, Shanghai, China, ⁴MR Research Collaboration, Siemens Healthineers Ltd., Shanghai, China, ⁵Institute of Science and Technology for Brain-Inspired Intelligence, Fudan Universit, Shanghai, China, ⁶ShanghaiTech University, Shanghai, China, ⁷Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ⁸Human Phenome Institute, Fudan University, Shanghai, China, ⁹Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence (Fudan University), Ministry of Education, Shanghai, China

Synopsis

Keywords: Functional/Dynamic, MSK, Chronic ankle instability, T2 mapping, quantitative MRI, Y-Balance Test

Motivation: This research is motivated by the need to clarify the unclear relationship between functional impairments and cartilage degeneration in chronic ankle instability (CAI), as previous studies have examined these factors separately.

Goal(s): This study compares CAI patients and controls to target interventions enhancing joint health and preventing cartilage degeneration.

Approach: This case-control study assessed CAI using Y-Balance Test, CoP analysis, MRI T2 mapping, and CAIT questionnaire for balance and instability.

Results: Higher T2 values in CAI indicate degeneration, correlating with poor CAIT scores, reduced YBT distances, and increased CoP excursions.

Impact: This study links CAI to functional impairments and cartilage degeneration, aiding targeted interventions to reduce long-term joint damage.

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