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Abstract #3032

A Cascaded Neural Network for Intravoxel Incoherent Motion Map Reconstruction

Liwen Jiang1, Haibin Xie1, Yinqiao Yi1, Lingjing Chen1, Ailing Wang1, and Guang Yang1
1East China Normal University, Shanghai, China

Synopsis

Keywords: Breast, IVIM

Motivation: Quantitative estimation of intravoxel incoherent motion (IVIM) maps is readily influenced by noise and artifacts in the DWI images and the processing time can be relatively high.

Goal(s): Use deep learning to improve the accuracy and robustness of parameter estimation for IVIM and speed up the computation.

Approach: We designed a simple cascaded network to reconstruct IVIM maps from noisy dMRI, consisting of one denoising network and one fitting network.

Results: Accurately reconstructed three parameter maps, f, D, and Ds, achieving the first place in the IVIM-dMRI Reconstruction Challenge hosted by AAPM.

Impact: With improved accuracy and robustness, IVIM maps can be used to assess tissue microstructural properties, which are critical to diagnosis of diseases, therapy planning and treatment responses assessment.

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