Abstract #3033

3D Renal Function Weighted Image using dual inversion recovery tissue-specific image contrast optimization (DIRECTION)

Kazuo Kodaira¹, Michinobu Nagao², Masami Yoneyama³, Yasutomo Katsumata³, Hiroshi Hamano³, Mana kato¹, Takumi Ogawa¹, Yutaka Hamatani¹, Isao shiina¹, Yasuhiro Goto¹, and Shuji Sakai²

¹Department of Radiological Services, Tokyo Women’s Medical University, Tokyo, Japan, ²Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women’s Medical University, Tokyo, Japan, ³Philips Japan, Ltd, Tokyo, Japan

Synopsis

Keywords: Kidney, Kidney, Renal function

Motivation: Various sequences have been proposed as renal-functional-MRI, including BOLD-MRI, IVIM-DWI, DTI and ASL.
However, analysis was complicated and the assessment was relatively difficult.
More simple and easily assessable approaches are required.

Goal(s): Our goal is to find more simple method of assessing renal-function from MR images.

Approach: We propose to assess renal-function by renal-corticomedullary-differentiation-image using 3D-TSE with dual-inversion-recovery-tissue-specific-image-contrast-optimization (DIRECTION).
Dual-TI were set to simultaneously suppress fat and blood signals, additionally resulting in high contrast in cortex and medulla.
We performed DIRECTION on 90 patients and investigated the correlation between renal-corticomedullary-contrast-ratio and eGFR.

Results: DIRECTION provided a strong correlation between renal-corticomedullary-contrast-ratio and eGFR.

Impact: DIRECTION had the potential to estimate renal function from the renal corticomedullary contrast ratio more simply than conventional methods. In addition, it could also assess anatomy by multi-slices with 3D scan.

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