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Abstract #3038

Discriminating tumor deposits and metastatic lymph nodes in rectal cancer with contrast-enhanced magnetic resonance imaging

Xue-han WU1, Yu-tao QUE2, Xin-yue YANG3, Zi-qiang WEN4, Yu-ru MA4, Yun-zhu WU5, Shen-ping YU4, Yi-yan LIU4, and Yan CHEN4
1Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China, 2The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, 3Zhujiang Hospital, Southern Medical University, Guangzhou, China, 4The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, 5Institute for AI in Medicine, School of Artificial Intelligence, Nanjing University of Information Science and Technology, Guangzhou, China

Synopsis

Keywords: Digestive, Digestive, Rectal neoplasms; Tumor deposits; Lymph node; Magnetic resonance imaging; Perfusion imaging

Motivation: Rectal cancer survival is impacted by local recurrence and metastasis. Risk factors included tumor deposits (TDs) and metastatic lymph nodes (MLNs).

Goal(s): To investigate the value of DCE-MRI parameters in distinguishing (TDs) from (MLNs) in rectal cancer, and to compare their effectiveness with T2WI and DWI.

Approach: In a retrospective analysis of 70 rectal cancer patients, 168 lesions were evaluated using DCE-MRI and DWI, focusing on parameters like Ktrans, kep, and ve.

Results: Significant differences between TDs and MLNs were found, with ve showing the highest AUC (0.772). A combined model improved diagnostic accuracy to an AUC of 0.833.

Impact: A combination of morphological features, DCE-MRI parameters, and ADC values can assist in preoperative differentiation between TDs and MLNs in rectal cancer.

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Keywords