Meeting Banner
Abstract #3044

In-vivo contrast enhanced T1 mapping for quantitative evaluation of intracranial atherosclerotic plaques

Xiaoqi Lin1, Xiaoming Liu2, Haozhong Sun1, Jiaqi Dou1, Ziming Xu1, Shuwan Yu1, and Huijun Chen1
1Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2Department of Radiology, Union Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan, China

Synopsis

Keywords: Atherosclerosis, Atherosclerosis, Vessel Wall Imaging

Motivation: T1 mapping has potential to surpass traditional T1w MR images as a quantitative biomarker for intracranial plaques. However T1 mapping's utility in clinical practice remain underexplored.

Goal(s): This study attempts to evaluate contrast-enhanced T1 mapping of intracranial plaques using 3D SNAP with golden angle radial k-space sampling (GOAL-SNAP) sequence.

Approach: Using the proposed method, this study compared T1 values between symptomatic and asymptomatic patients with atherosclerotic plaques in the middle cerebral artery (MCA).

Results: Findings reveal significant distinctions between T1 values from symptomatic and asymptomatic patients (804.20±211.06 vs. 1176.45±267.35, p=0.029).

Impact: The proposed approach shows promise in advancing our comprehension of intracranial atherosclerosis and its clinical implications, more patients are being recruited for further validation.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords