Abstract #3055

An Open Source Motion-compensated Cardiac Diffusion Sequence Validated Across Different MRI Systems and Gradient Strengths

Eric Arbes¹, Simon Reiss¹, Ariel Hannum², Johannes Fischer¹, Qingping Chen¹, and Michael Bock¹

¹Dept. of Radiology – Medical Physics, University Medical Center Freiburg, University of Freiburg, Freiburg im Breisgau, Germany, ²Department of Radiology, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Cardiac Diffusion MRI results are difficult to compare due to variations in pulse sequence implementation.

Goal(s): To develop an open source second order motion compensated cardiac diffusion sequence that can be applied reproducibly at different MRI systems.

Approach: The sequence was developed using the open source sequence development platform Pulseq. Diffusion gradients optimized for different gradient strengths were tested on three volunteers across three different MRI systems.

Results: DWI and DTI data could be acquired at all systems, and a systematic comparison revealed hardware-based performance differences.

Impact: The sequence allows for consistent and comparable application of cardiac diffusion MRI at different MRI systems and field strengths enabling standardized multi-center studies and cross-vendor cooperation.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.