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Abstract #3125

Lumbar disc degeneration is significant correlated with lumbar spine volumetric BMD in male patients with NSLBP, except for the L5/S1 disc

Xihan Xiang1, Yan Zhang1, Ze Li1, Huilou Liang2, and Junrong Chen3
1Chengdu Sport University, Chengdu, China, 2GE HealthCare MR Research, Beijing, China, 3Sichuan Province Orthopedic Hospital, Chengdu, China

Synopsis

Keywords: Bone/Skeletal, Skeletal

Motivation: Lumbar disc degeneration (LDD) and osteoporosis (OP) are both possible contributors to non-specific low back pain (NSLBP). However, the relationship between LDD and volumetric bone mineral density (vBMD) used to assess OP remains unclear in men.

Goal(s): To investigate the relationship between LDD and vBMD in male NSLBP patients.

Approach: We assessed the relationship between the extent of LDD, obtained from MRI, and vBMD of vertebral bodies, measured using quantitative CT, in male NSLBP patients.

Results: Our results showed that LDD was negatively correlated with vBMD in male NSLBP patients, with the L1/2-L4/5 disc being an independent influencing factor of vBMD.

Impact: L1/2-L4/5 disc being an independent influencing factor of vBMD in male NSLBP patients. Further investigation can explore if the degree of L1/2-L4/5 intervertebral disc degeneration through MRI can predict OP, thereby reducing the occurrence of complications such as osteoporotic fractures.

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