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Abstract #3199

3D-EPI SWI at 0.5T

Yishen Gao1, Yuan Lian1, Yuanchen Jiang1, Jingzhe Liu2,3, Zhengyuan Huang4, Yang Ye4, and Hua Guo1
1Center for Biomedical Imaging Research, School of Biomedical Engineering, Tsinghua University, Beijing, China, 2Department of Radiology, The First Affiliated Hospital of Tsinghua University, Beijing, China, 3School of Clinical Medicine, Tsinghua University, Beijing, China, 4Marvel Stone Healthcare Co. Ltd., Wuxi, China

Synopsis

Keywords: Image Reconstruction, Low-Field MRI, EPI-SWI

Motivation: 3D-EPI has shown great potential for susceptibility weighted imaging (SWI) on high field MRI due to its high sampling efficiency. It may be feasible to achieve fast and superior quality for SWI at low-field strength.

Goal(s): To optimize a 3D-EPI SWI sequence at 0.5T for reasonable resolution and good SNR, as well as suppression of Nyquist ghost.

Approach: A multi-shot 3D-EPI sequence was used to acquire SWI data, with acquisition parameters tuned based on literature. Linear phase correction and dual-polarity GRAPPA were used to remove Nyquist ghost.

Results: 3D-EPI demonstrated good sensitivity to susceptibility difference in brain tissue on 0.5T.

Impact: 0.5T with 3D-EP-SWI offers greater access than higher field strength MRI, and may meet clinical needs for diagnosis of cerebral diseases like cerebral microbleeds.

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