Meeting Banner
Abstract #3502

Comprehensive CFD Analysis of Hemodynamic Patterns in Atherosclerosis: Implications of ICA Stenosis Severity on Head and Neck Dynamics

Yaxuan Wu1, Jing Ding1, Shuang Xia2, and Yu Guo2
1The School of Medicine, Nankai University, Tianjin, China, 2Department of Radiology, Tianjin First Central Hospital, Nankai University, Tianjin, China

Synopsis

Keywords: Atherosclerosis, Atherosclerosis

Motivation: This study uses a CFD-based holistic hemodynamic analysis approach to overcome the limitations of localized CFD analyses.

Goal(s): To enable comprehensive evaluation of AS-related hemodynamic parameters in the head and neck.

Approach: Through hemodynamic simulation modeling and a quartile-based method, clinically significant regions in the ICA-M1 segment were identified and analyzed between moderate and severe stenosis groups at the ICA origin.

Results: Results show that with increasing ICA stenosis severity, low TAWSS regions expand, average TAWSS in these regions decreases, and mean RRT in high RRT regions rises, suggesting that severe ICA stenosis promotes plaque formation and instability across the ICA-M1 segment.

Impact: The proposed CFD-based approach identifies hemodynamic patterns linked to AS risk and progression, offering insights into how ICA stenosis severity impacts head and neck hemodynamics, guiding clinicians in patient assessment and management.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords