Abstract #3519

Efficient distortion-free multi-contrast body imaging with Water/Fat Separated Echo Planar Time-resolved Imaging

Zhangxuan Hu^1,2, Timothy G. Reese^1,2, Jian Wu^1,2, Lawrence L. Wald^1,2,3, Jonathan R. Polimeni^1,2,3, Zijing Dong^1,2, and Fuyixue Wang^1,2

¹Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ²Department of Radiology, Harvard Medical School, Boston, MA, United States, ³Harvard-MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

Synopsis

Keywords: Fat & Fat/Water Separation, Fat and Fat/Water Separation

Motivation: Water/fat-separated Echo-Planar Time-resolved Imaging (WFS-EPTI) can produce distortion-free multi-contrast images with high efficiency in the presence of fat tissues. The efficacy of WFS-EPTI has been demonstrated in phantom and brain. Extensions to body imaging are desired.

Goal(s): Achieving efficient fat-artifact-free multi-contrast body imaging with WFS-EPTI.

Approach: A joint reconstruction approach was proposed for WFS-EPTI to improve the performance in body imaging. Regularization and calibration strategies used in WFS-EPTI were optimized, particularly for regions with high B0 inhomogeneity and prevalent fat signals.

Results: Experimental results demonstrated the efficacy of WFS-EPTI for water/fat separation and multi-contrast/quantitative imaging with minimal fat-induced artifacts in body imaging applications.

Impact: The proposed WFS-EPTI effectively separates water and fat signals, while providing efficient acquisition of high-resolution, distortion-free multi-contrast images with minimal fat-induced artifacts. The feasibility of WFS-EPTI in body imaging was demonstrated.

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